Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1993-9-17
pubmed:abstractText
Virulence, as determined in a mouse model, and the virulence factor activities of catalase, superoxide dismutase, and listeriolysin O were examined in a parental strain (10403S) and in a nonhemolytic mutant strain (DP-L224) of Listeria monocytogenes. The cells were propagated in media containing various concentrations of sodium chloride or potassium chloride. Strains 10403S and DP-L224 exhibited significant increases in catalase activity and listeriolysin O activity when grown in medium containing either salt at 428 mM. The superoxide dismutase activities for both strains increased when they were grown in medium containing either salt. The superoxide dismutase activity was significantly increased only when cells were propagated in medium containing no salt compared with that when they were propagated in medium containing either salt at 1,112 mM. In addition, the listeriolysin O activity was highest for cells propagated in medium containing KCl at 428 mM, while the activity was significantly less for cells propagated in medium containing NaCl at an equal concentration. Virulence was examined in mouse livers and spleens after intravenous infection, and approximate 50% lethal doses were determined after intragastric and intraperitoneal infection. Each method of infection indicated that listeriolysin O is required for virulence, while growth in salt-containing medium or the production of higher levels of catalase, superoxide dismutase, and listeriolysin O do not appear to enhance the virulence of L. monocytogenes.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/8357245-110685, http://linkedlifedata.com/resource/pubmed/commentcorrection/8357245-1312514, http://linkedlifedata.com/resource/pubmed/commentcorrection/8357245-13948140, http://linkedlifedata.com/resource/pubmed/commentcorrection/8357245-1729245, http://linkedlifedata.com/resource/pubmed/commentcorrection/8357245-1732227, http://linkedlifedata.com/resource/pubmed/commentcorrection/8357245-2117576, http://linkedlifedata.com/resource/pubmed/commentcorrection/8357245-2125816, http://linkedlifedata.com/resource/pubmed/commentcorrection/8357245-2509366, http://linkedlifedata.com/resource/pubmed/commentcorrection/8357245-2515411, http://linkedlifedata.com/resource/pubmed/commentcorrection/8357245-2516113, http://linkedlifedata.com/resource/pubmed/commentcorrection/8357245-2545629, http://linkedlifedata.com/resource/pubmed/commentcorrection/8357245-2824384, http://linkedlifedata.com/resource/pubmed/commentcorrection/8357245-2833557, http://linkedlifedata.com/resource/pubmed/commentcorrection/8357245-3121515, http://linkedlifedata.com/resource/pubmed/commentcorrection/8357245-3123396, http://linkedlifedata.com/resource/pubmed/commentcorrection/8357245-3128167, http://linkedlifedata.com/resource/pubmed/commentcorrection/8357245-3143518, http://linkedlifedata.com/resource/pubmed/commentcorrection/8357245-3144573, http://linkedlifedata.com/resource/pubmed/commentcorrection/8357245-3279032, http://linkedlifedata.com/resource/pubmed/commentcorrection/8357245-3755069, http://linkedlifedata.com/resource/pubmed/commentcorrection/8357245-3919119, http://linkedlifedata.com/resource/pubmed/commentcorrection/8357245-6772561, http://linkedlifedata.com/resource/pubmed/commentcorrection/8357245-6775446, http://linkedlifedata.com/resource/pubmed/commentcorrection/8357245-6779690, http://linkedlifedata.com/resource/pubmed/commentcorrection/8357245-7365456, http://linkedlifedata.com/resource/pubmed/commentcorrection/8357245-812294
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0099-2240
pubmed:author
pubmed:issnType
Print
pubmed:volume
59
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2082-6
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Sodium chloride, potassium chloride, and virulence in Listeria monocytogenes.
pubmed:affiliation
Department of Food Science, University of Illinois, Urbana 61801.
pubmed:publicationType
Journal Article