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rdf:type |
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lifeskim:mentions |
umls-concept:C0007634,
umls-concept:C0017262,
umls-concept:C0017337,
umls-concept:C0079323,
umls-concept:C0185117,
umls-concept:C0205307,
umls-concept:C0301625,
umls-concept:C0443199,
umls-concept:C0679058,
umls-concept:C1510411,
umls-concept:C1547699,
umls-concept:C2700640,
umls-concept:C2911684
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pubmed:dateCreated |
1993-9-21
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pubmed:abstractText |
A subtraction hybridization technique was used to identify genes specifically expressed in phenotypic revertants derived from cells transformed by the H-ras oncogene. The expression of genes coding for components of the extracellular matrix appears to be frequently down-regulated in transformed cells. Partial restoration is associated with the reexpression of the normal phenotype in revertants.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0065-2571
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
267-80
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8356912-Animals,
pubmed-meshheading:8356912-Base Sequence,
pubmed-meshheading:8356912-Cell Line, Transformed,
pubmed-meshheading:8356912-Cell Transformation, Neoplastic,
pubmed-meshheading:8356912-Collagen,
pubmed-meshheading:8356912-DNA,
pubmed-meshheading:8356912-Down-Regulation,
pubmed-meshheading:8356912-Gene Expression Regulation,
pubmed-meshheading:8356912-Genes, ras,
pubmed-meshheading:8356912-Humans,
pubmed-meshheading:8356912-Mice,
pubmed-meshheading:8356912-Molecular Sequence Data,
pubmed-meshheading:8356912-Phenotype,
pubmed-meshheading:8356912-Procollagen,
pubmed-meshheading:8356912-Rats,
pubmed-meshheading:8356912-Sequence Alignment,
pubmed-meshheading:8356912-Sequence Tagged Sites
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pubmed:year |
1993
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pubmed:articleTitle |
Suppression of ras-mediated transformation. Differential expression of genes encoding extracellular matrix proteins in normal, transformed and revertant cells.
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pubmed:affiliation |
Department of Pathology, University of Zürich, Switzerland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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