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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
1977-3-31
|
| pubmed:abstractText |
Using a solid phase radioimmunoassay, prevalence of anti-HA was determined in sera of 661 German patients treated following accidents, 70 persons born in Mediterranean countries and 175 persons from Lillehammer, Norway. In Germany (55% positive) an increase in prevalence of anti-HA from 13% in the group below 20 years of age to 92% in persons over 49 was noted. This and further data suggest that after infection anti-HA is detectable for life. Persons from Norway (17% positive) aged below 40 years had a low prevalence of anti-HA (4-10%), whereas even young persons from Mediterranean countries (81% positive) hat antibody in about 80% of cases. Prevalence rates in different age groups suggest a remarkable decrease in incidence of hepatitis A infection over the last three decades in Germany. This results in a rise in the mean age at which hepatitis A infection is acquired and high morbidity during travel abroad. Only one of 10 hepatitis A infections appears to produce clinical disease. Young anti-HA positive individuals exhibit higher titers on average than older ones.
|
| pubmed:language |
ger
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0036-7672
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
5
|
| pubmed:volume |
107
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
129-33
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading | |
| pubmed:year |
1977
|
| pubmed:articleTitle |
[Frequency of hepatitis A antibodies in populations of various European countries].
|
| pubmed:publicationType |
Journal Article,
English Abstract
|