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pubmed-article:8340604pubmed:abstractTextThe presence of mutants of the precore region of the hepatitis B virus genome was investigated in French patients with fulminant hepatitis. Only one of the 10 subjects had a detectable mutation by direct sequencing. On the other hand, 2/10 and 3/10 had evidence of coinfection by hepatitis D virus and hepatitis C virus. These results indicate that the precore stop mutation at codon 28 is not a general condition in fulminant hepatitis B and might reflect epidemiological factors.lld:pubmed
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pubmed-article:8340604pubmed:articleTitleLow prevalence of precore mutations in hepatitis B virus DNA in fulminant hepatitis type B in France.lld:pubmed
pubmed-article:8340604pubmed:affiliationHybridotest, Institut Pasteur, Paris, France.lld:pubmed
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