rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
1
|
pubmed:dateCreated |
1993-8-31
|
pubmed:abstractText |
The presence of mutants of the precore region of the hepatitis B virus genome was investigated in French patients with fulminant hepatitis. Only one of the 10 subjects had a detectable mutation by direct sequencing. On the other hand, 2/10 and 3/10 had evidence of coinfection by hepatitis D virus and hepatitis C virus. These results indicate that the precore stop mutation at codon 28 is not a general condition in fulminant hepatitis B and might reflect epidemiological factors.
|
pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0168-8278
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
18
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
119-22
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:8340604-Adult,
pubmed-meshheading:8340604-Base Sequence,
pubmed-meshheading:8340604-DNA, Viral,
pubmed-meshheading:8340604-Female,
pubmed-meshheading:8340604-France,
pubmed-meshheading:8340604-Hepatic Encephalopathy,
pubmed-meshheading:8340604-Hepatitis B,
pubmed-meshheading:8340604-Hepatitis B virus,
pubmed-meshheading:8340604-Humans,
pubmed-meshheading:8340604-Liver Transplantation,
pubmed-meshheading:8340604-Male,
pubmed-meshheading:8340604-Molecular Sequence Data,
pubmed-meshheading:8340604-Mutation,
pubmed-meshheading:8340604-Prevalence,
pubmed-meshheading:8340604-Retrospective Studies
|
pubmed:year |
1993
|
pubmed:articleTitle |
Low prevalence of precore mutations in hepatitis B virus DNA in fulminant hepatitis type B in France.
|
pubmed:affiliation |
Hybridotest, Institut Pasteur, Paris, France.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|