Linked Life Data

8335597

Source:http://linkedlifedata.com/resource/pubmed/id/8335597

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1993-8-26
pubmed:abstractText
Complex demodulation of the T wave permits tracking of susceptibility to ventricular fibrillation under the clinically relevant conditions of acute myocardial ischemia and reperfusion. To facilitate the processing and to increase the applicability of the methods, we have developed algorithms and applied mathematical transformations that can be carried out with a personal computer. The program is self-contained and menu driven and transforms the data into a three-dimensional graphic display of magnitude of alternans (mV x ms), time in the cardiac cycle, and duration of the assessment. It is suitable for investigations with diverse experimental procedures such as coronary artery occlusion and release, autonomic interventions, behavioral stress testing, and drug administration. Our methodology may be employed in clinical conditions such as postmyocardial infarction. Prinzmetal's angina, and the long QT syndrome, wherein T wave alternans has been reported in body surface leads. Ultimately, T wave alternans analysis with use of the personal computer system may help guide therapeutic interventions.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
8750-7587
pubmed:author
pubmed:issnType
Print
pubmed:volume
74
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2606-12
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Personal computer system for tracking cardiac vulnerability by complex demodulation of the T wave.
pubmed:affiliation
Department of Pharmacology, Georgetown University School of Medicine, Washington, DC 20007.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.