Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1993-8-11
pubmed:abstractText
Authors refer results obtained in 24 cases of primary NHL of gastrointestinal tract. These cases were observed in the period 1981-1990. All cases can be included as primary extranodal lymphomas satisfying criteria of the literature. Sixty-six per cent (16/24) had a gastric localization half cases were centrocytic-centroblastic lymphomas followed by immunoblastic, centroblastic, follicular centrocytic-centroblastic and lymphocytic-well-differentiated. In intestinal localisation (34% of cases), the most represented was lymphocytic poor-differentiated, followed by mixed centrocytic lymphoma. Therapeutic strategy was: surgery in all patients followed by chemotherapy (CHOP 14/24) or by radiotherapy plus chemotherapy (8/24). Surgery alone was adopted in 2 out 24 patients. Patients who received radiotherapy plus chemotherapy had a sandwich treatment (CVP = 4/8, CHOP = 4/8) consisting of splint course of 3 cycles followed by radiotherapy and completed with other 3 drugs cycles. Sixteen out 24 patients were valuable (4 patients were lost during the follow-up due to problems other than the disease; 4 patients are still under treatment). In the 16 valuable patients we had a complete remission (CR) with a median free-disease survival of 82 months (range: 12-116 months) by means of the primary treatment. Four out 16 patients relapsed. In these patients the free-disease survival was range 8-108 months. All patients reached a second CR by means of chemotherapy (CCNU + VIP16) or radiotherapy. No cases of second tumor insorgence was observed.
pubmed:language
ita
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0026-4733
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
48
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
325-30
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:8327178-Adult, pubmed-meshheading:8327178-Aged, pubmed-meshheading:8327178-Antineoplastic Combined Chemotherapy Protocols, pubmed-meshheading:8327178-Chemotherapy, Adjuvant, pubmed-meshheading:8327178-Combined Modality Therapy, pubmed-meshheading:8327178-Cyclophosphamide, pubmed-meshheading:8327178-Doxorubicin, pubmed-meshheading:8327178-Female, pubmed-meshheading:8327178-Follow-Up Studies, pubmed-meshheading:8327178-Gastrointestinal Neoplasms, pubmed-meshheading:8327178-Humans, pubmed-meshheading:8327178-Lymphoma, Non-Hodgkin, pubmed-meshheading:8327178-Male, pubmed-meshheading:8327178-Middle Aged, pubmed-meshheading:8327178-Neoplasm Recurrence, Local, pubmed-meshheading:8327178-Neoplasm Staging, pubmed-meshheading:8327178-Postoperative Care, pubmed-meshheading:8327178-Prednisone, pubmed-meshheading:8327178-Remission Induction, pubmed-meshheading:8327178-Vincristine
pubmed:year
1993
pubmed:articleTitle
[Case histories of extranodal non-Hodgkin's lymphomas with primary gastrointestinal appearance].
pubmed:affiliation
Ospedale Civile S. Maria dei Battuti, Regione Friuli-Venezia Giulia--USL 9, Sanvitese.
pubmed:publicationType
Journal Article, English Abstract