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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
1993-8-11
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pubmed:abstractText |
Authors refer results obtained in 24 cases of primary NHL of gastrointestinal tract. These cases were observed in the period 1981-1990. All cases can be included as primary extranodal lymphomas satisfying criteria of the literature. Sixty-six per cent (16/24) had a gastric localization half cases were centrocytic-centroblastic lymphomas followed by immunoblastic, centroblastic, follicular centrocytic-centroblastic and lymphocytic-well-differentiated. In intestinal localisation (34% of cases), the most represented was lymphocytic poor-differentiated, followed by mixed centrocytic lymphoma. Therapeutic strategy was: surgery in all patients followed by chemotherapy (CHOP 14/24) or by radiotherapy plus chemotherapy (8/24). Surgery alone was adopted in 2 out 24 patients. Patients who received radiotherapy plus chemotherapy had a sandwich treatment (CVP = 4/8, CHOP = 4/8) consisting of splint course of 3 cycles followed by radiotherapy and completed with other 3 drugs cycles. Sixteen out 24 patients were valuable (4 patients were lost during the follow-up due to problems other than the disease; 4 patients are still under treatment). In the 16 valuable patients we had a complete remission (CR) with a median free-disease survival of 82 months (range: 12-116 months) by means of the primary treatment. Four out 16 patients relapsed. In these patients the free-disease survival was range 8-108 months. All patients reached a second CR by means of chemotherapy (CCNU + VIP16) or radiotherapy. No cases of second tumor insorgence was observed.
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pubmed:language |
ita
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0026-4733
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
325-30
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8327178-Adult,
pubmed-meshheading:8327178-Aged,
pubmed-meshheading:8327178-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:8327178-Chemotherapy, Adjuvant,
pubmed-meshheading:8327178-Combined Modality Therapy,
pubmed-meshheading:8327178-Cyclophosphamide,
pubmed-meshheading:8327178-Doxorubicin,
pubmed-meshheading:8327178-Female,
pubmed-meshheading:8327178-Follow-Up Studies,
pubmed-meshheading:8327178-Gastrointestinal Neoplasms,
pubmed-meshheading:8327178-Humans,
pubmed-meshheading:8327178-Lymphoma, Non-Hodgkin,
pubmed-meshheading:8327178-Male,
pubmed-meshheading:8327178-Middle Aged,
pubmed-meshheading:8327178-Neoplasm Recurrence, Local,
pubmed-meshheading:8327178-Neoplasm Staging,
pubmed-meshheading:8327178-Postoperative Care,
pubmed-meshheading:8327178-Prednisone,
pubmed-meshheading:8327178-Remission Induction,
pubmed-meshheading:8327178-Vincristine
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pubmed:year |
1993
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pubmed:articleTitle |
[Case histories of extranodal non-Hodgkin's lymphomas with primary gastrointestinal appearance].
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pubmed:affiliation |
Ospedale Civile S. Maria dei Battuti, Regione Friuli-Venezia Giulia--USL 9, Sanvitese.
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pubmed:publicationType |
Journal Article,
English Abstract
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