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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:dateCreated |
1977-3-31
|
| pubmed:abstractText |
A study was made of the elimination of fosfomycin by the membrane of the artificial kidney in 10 patients with hemodialysis and a creatinine clearance of less than 5 ml/min. To do so we determined the half-life, the dialysance, the percentage of total loss and the percentage of loss by the artificial kidney. We reached the conclusion that fosfomycin is heavily dialyzed (D = 64 ml/min), it is entirely eliminated by the kidneys and its half-life is therefore affected very little (an increase of only about 30 min is produced). All of this leads to a practical schema by which the entire initial dose should be replenished at the end of each dialysis.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0009-3157
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
23 Suppl 1
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
210-6
|
| pubmed:dateRevised |
2009-11-11
|
| pubmed:meshHeading |
pubmed-meshheading:832518-Anti-Bacterial Agents,
pubmed-meshheading:832518-Fosfomycin,
pubmed-meshheading:832518-Half-Life,
pubmed-meshheading:832518-Humans,
pubmed-meshheading:832518-Kidney,
pubmed-meshheading:832518-Membranes, Artificial,
pubmed-meshheading:832518-Renal Dialysis,
pubmed-meshheading:832518-Time Factors
|
| pubmed:year |
1977
|
| pubmed:articleTitle |
Pharmacokinetics of fosfomycin during hemodialysis.
|
| pubmed:publicationType |
Journal Article
|