rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
1993-8-5
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pubmed:abstractText |
Previous investigations suggest that dietary sources of polycyclic aromatic hydrocarbons (PAHs) contribute to the PAH-DNA adduct load in peripheral white blood cells (WBCs). In the current study, we measured PAH-DNA adducts by enzyme-linked immunosorbent assay in WBCs obtained from 47 California wildland (forest) firefighters at two time points (early and late) during an active forest fire season. PAH-DNA adduct levels were not associated with recent firefighting activity, but were positively associated with frequency of charbroiled food consumption in the previous 2 weeks. In addition, adduct levels declined with time since last ingestion of charbroiled food. These studies indicate that recent consumption of charbroiled food contributes to the PAH-DNA adduct load in peripheral WBCs.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0091-6765
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
99
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
265-7
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:8319640-Adolescent,
pubmed-meshheading:8319640-Adult,
pubmed-meshheading:8319640-DNA,
pubmed-meshheading:8319640-Diet,
pubmed-meshheading:8319640-Female,
pubmed-meshheading:8319640-Fires,
pubmed-meshheading:8319640-Food Contamination,
pubmed-meshheading:8319640-Hot Temperature,
pubmed-meshheading:8319640-Humans,
pubmed-meshheading:8319640-Leukocytes,
pubmed-meshheading:8319640-Male,
pubmed-meshheading:8319640-Middle Aged,
pubmed-meshheading:8319640-Occupational Exposure,
pubmed-meshheading:8319640-Polycyclic Compounds
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pubmed:year |
1993
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pubmed:articleTitle |
Association of PAH-DNA adducts in peripheral white blood cells with dietary exposure to polyaromatic hydrocarbons.
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pubmed:affiliation |
Epidemiology and Biostatistics Program, National Cancer Institute, Bethesda, MD 20892.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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