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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1994-3-18
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pubmed:abstractText |
Heparin inhibits proliferation of smooth muscle cells in culture and intimal hyperplasia in experimental animals but paradoxically exacerbates vascular injury in clinical trials. To determine whether the difference in the means by which heparin was administered explained the benefit in animals and aggravation in humans, we examined the vascular effects of a range of heparin treatments.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0009-7322
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
89
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
770-6
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:8313565-Animals,
pubmed-meshheading:8313565-Arteries,
pubmed-meshheading:8313565-Arteriosclerosis,
pubmed-meshheading:8313565-Balloon Dilation,
pubmed-meshheading:8313565-Blood Coagulation,
pubmed-meshheading:8313565-Cell Division,
pubmed-meshheading:8313565-Drug Administration Schedule,
pubmed-meshheading:8313565-Heparin,
pubmed-meshheading:8313565-Hyperplasia,
pubmed-meshheading:8313565-Infusion Pumps,
pubmed-meshheading:8313565-Infusions, Intravenous,
pubmed-meshheading:8313565-Injections, Subcutaneous,
pubmed-meshheading:8313565-Rats,
pubmed-meshheading:8313565-Rats, Sprague-Dawley,
pubmed-meshheading:8313565-Recurrence,
pubmed-meshheading:8313565-Thrombosis,
pubmed-meshheading:8313565-Tunica Intima
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pubmed:year |
1994
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pubmed:articleTitle |
Contrasting effects of the intermittent and continuous administration of heparin in experimental restenosis.
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pubmed:affiliation |
Department of Medicine (Cardiovascular Division, Brigham and Women's Hospital), Boston, MA 02115.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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