Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1994-3-17
|
pubmed:databankReference | |
pubmed:abstractText |
A novel human gene (sazD) that maps to the autosomal dominant polycystic kidney disease region shares sequence similarity with members of the beta-transducin superfamily. The cDNA sazD-c predicts an approximately 58-kDa protein (sazD) with seven internal repeats, similar to the WD-40 motif of the transducin family. The size of this protein family has been expanding rapidly; however, neither the structure nor the function of this repeated motif is known. Preliminary data do not suggest that sazD is mutated in patients with polycystic kidney disease.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0888-7543
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
18
|
pubmed:geneSymbol |
sazD,
sazD-c
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
709-11
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:8307582-Adult,
pubmed-meshheading:8307582-Amino Acid Sequence,
pubmed-meshheading:8307582-Base Sequence,
pubmed-meshheading:8307582-Chromosome Mapping,
pubmed-meshheading:8307582-Consensus Sequence,
pubmed-meshheading:8307582-Humans,
pubmed-meshheading:8307582-Kidney,
pubmed-meshheading:8307582-Molecular Sequence Data,
pubmed-meshheading:8307582-Multigene Family,
pubmed-meshheading:8307582-Mutation,
pubmed-meshheading:8307582-Polycystic Kidney, Autosomal Dominant,
pubmed-meshheading:8307582-Repetitive Sequences, Nucleic Acid,
pubmed-meshheading:8307582-Sequence Homology, Amino Acid,
pubmed-meshheading:8307582-Transducin
|
pubmed:year |
1993
|
pubmed:articleTitle |
A transducin-like gene maps to the autosomal dominant polycystic kidney disease gene region.
|
pubmed:affiliation |
Department of Genetics, Yale University School of Medicine, New Haven, Connecticut.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|