Linked Life Data

8290496

Source:http://linkedlifedata.com/resource/pubmed/id/8290496

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1994-2-23
pubmed:abstractText
The contractile properties of the umbilical artery to oxygen, U46619 (a stable thromboxane A2 mimetic) and 5-hydroxytryptamine (5-HT) were studied in normal term (> or = 37 weeks) and preterm (< 34 weeks) pregnancies, and in a group of pregnancies complicated by intrauterine growth retardation (IUGR). Isometric contractile responses in the preterm group to oxygen were reduced when compared with the term group, though no differences were found between these groups in the responses to either U46619 or 5-HT. In the IUGR group the responses to oxygen did not differ from gestationally matched normal pregnancies, though among those cases delivered preterm, the finding of absent end-diastolic flow velocity in the umbilical artery prior to delivery was associated with markedly diminished responses to oxygen. These data indicate the development of oxygen-induced contractions in the umbilical artery as pregnancy advances, which may fail to function in the severely growth-retarded fetus.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0143-4004
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
563-70
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Contractile responses of the human umbilical artery from pregnancies complicated by intrauterine growth retardation.
pubmed:affiliation
Autonomic Physiology Unit, University of Glasgow, Scotland.
pubmed:publicationType
Journal Article, In Vitro, Research Support, Non-U.S. Gov't