Linked Life Data

8289996

Source:http://linkedlifedata.com/resource/pubmed/id/8289996

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1994-2-22
pubmed:abstractText
The effects of recombinant human erythropoietin (rHuEPO) on survival and blood pressure in hypovolemic hemorrhagic shock in rats have been studied by intravenous administration. The hormone caused an increase in the time of survival compared to the group of rats without treatment (102 +/- 4.5 vs. 25 +/- 4.5 min, p < 0.01, vehicle; 102 +/- 4.5 vs. 25 +/- 2 min, p < 0.01, saline solution) and an increase in the percentage of the surviving animals (5/7 after 120 min vs. 0/7, p < 0.05). The animals treated showed an increase in mean arterial pressure that was not present in the control group. Through their data, the authors suggest the vasopressor effect of erythropoietin. Furthermore, from other studies done before, they hypothesize that the vasoactive ability of the hormone is endothelin mediated.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0028-2766
pubmed:author
pubmed:issnType
Print
pubmed:volume
65
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
440-3
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Effects of intravenous administration of recombinant human erythropoietin in rats subject to hemorrhagic shock.
pubmed:affiliation
Department of Internal Medicine, University of Messina, Italy.
pubmed:publicationType
Journal Article