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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2 Pt 1
|
pubmed:dateCreated |
1977-3-31
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pubmed:abstractText |
A clinical trial was performed to test a loading dose regimen of tetracycline (1.5 gm po sTAT and 0.5 mg po quid for 4 days) against a no-loading dose (0.5 gm po quid for 4 1/2 days) in the treatment of 477 cases of uncomplicated male urogenital gonorrhea. The regimens were equivalent, with an overall cure rate of 96%. A crossover pharmacokinetic study in 10 healthy volunteers demonstrated higher blood levels during the first day on the loading regimen, but equivalence thereafter. Tetracycline, in a total dose of 9.5 gm, is highly effective treatment, and a loading dose is not necessary.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0095-148X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
3
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
56-8
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:827538-Adult,
pubmed-meshheading:827538-Clinical Trials as Topic,
pubmed-meshheading:827538-Gonorrhea,
pubmed-meshheading:827538-Humans,
pubmed-meshheading:827538-Male,
pubmed-meshheading:827538-Microbial Sensitivity Tests,
pubmed-meshheading:827538-Neisseria gonorrhoeae,
pubmed-meshheading:827538-Tetracycline
|
pubmed:year |
1976
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pubmed:articleTitle |
Tetracycline in the treatment of uncomplicated male gonorrhea.
|
pubmed:publicationType |
Journal Article,
Clinical Trial
|