Linked Life Data

8263659

Source:http://linkedlifedata.com/resource/pubmed/id/8263659

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1994-1-26
pubmed:abstractText
A parenteral admixture composed of 25% of 20% Intralipid, 25% of Azonutril 25, 37.5% of 30% Glucose and 12.5% of 50% Glucose was supplemented with copper, iron and zinc in the organic (gluconate) or inorganic (chloride) form at the following usual final concentrations: copper 0.24 mg/L, iron 0.50 mg/L, zinc 2.00 mg/L. The mixture was stored at 4 degrees C and at 25 degrees C for 24, 48, and 72 hours, and for one week. Determination of the pH indicated good stability of the mixture containing the trace elements in the gluconate form. A significant decrease in the pH of the mixture containing the trace elements as chlorides was noted after one week of storage at both temperatures. Particle size analysis revealed no significant variations between the two formulations after one week of storage. Flocculation kinetics confirmed the results obtained with the other two methods used to determine physicochemical stability. In addition, the kinetics indicated that the possibilities of coalescence processes are highly reduced in all cases. It may be concluded that the two type of mixtures remain stable for Seven days at 4 degrees C and 25 degrees C. However, mixtures containing trace elements in gluconate form should be chosen in cases of longer storage.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0279-7976
pubmed:author
pubmed:issnType
Print
pubmed:volume
47
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
199-204
pubmed:dateRevised
2000-12-18
pubmed:meshHeading
pubmed:articleTitle
Influence of copper, iron, and zinc on the physicochemical properties of parenteral admixture.
pubmed:affiliation
Laboratoire de Biochimie C, Hôpital A. Michallon, Grenoble, France.
pubmed:publicationType
Journal Article