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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1994-1-21
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pubmed:abstractText |
To evaluate serum tetranectin as a prognostic marker before first-line chemotherapy, serum levels were studied in 67 patients with metastatic breast cancer. In the Cox analyses, the relative risk (RR) for death of cancer varied with the cut-off level of serum tetranectin. A maximal RR of 5.0 was found for patients with serum tetranectin < or = 5.4 mg/l. The maximal RR of death for the other prognostic variables were multiple metastases 2.8, and for a poor performance status 2.0. Testing for the outcome, progressive disease, a maximal RR of 3.8 was found for patients with serum tetranectin < or = 5.3 mg/l, a maximal RR of 3.7 for multiple metastases and a maximal RR of 1.8 for a poor performance status. Significantly lower serum tetranectin values were found in patients with a poor treatment response compared to well responding patients. Serum tetranectrin seems to be useful as an additional prognostic factor in metastatic breast cancer.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0284-186X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
32
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
631-6
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pubmed:dateRevised |
2009-5-12
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pubmed:meshHeading |
pubmed-meshheading:8260181-Adult,
pubmed-meshheading:8260181-Aged,
pubmed-meshheading:8260181-Biological Markers,
pubmed-meshheading:8260181-Blood Proteins,
pubmed-meshheading:8260181-Breast Neoplasms,
pubmed-meshheading:8260181-Humans,
pubmed-meshheading:8260181-Lectins, C-Type,
pubmed-meshheading:8260181-Middle Aged,
pubmed-meshheading:8260181-Neoplasm Metastasis,
pubmed-meshheading:8260181-Prognosis,
pubmed-meshheading:8260181-Survival Analysis
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pubmed:year |
1993
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pubmed:articleTitle |
Prognostic value of serum tetranectin in patients with metastatic breast cancer.
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pubmed:affiliation |
Department of Clinical Biochemistry, Statens Seruminstitut Copenhagen, Denmark.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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