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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
1994-1-11
|
| pubmed:abstractText |
We report a patient with Fanconi's anaemia and multiple lesions of vulvo-anal Bowen's disease. She was thrombocytopenic and lymphopenic, and NK-mediated cytotoxicity was undetectable. The vulvar lesions did not contain papillomavirus DNA. In vitro studies showed a possible benefit from acitretin treatment on bone marrow stem cells. However, low-dose acitretin given for 14 months did not prevent the development of an anal squamous carcinoma. Acitretin therapy was, however, associated with a sustained rise in the platelet count.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
0007-0963
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
129
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
615-8
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:8251364-Adult,
pubmed-meshheading:8251364-Anus Neoplasms,
pubmed-meshheading:8251364-Bowen's Disease,
pubmed-meshheading:8251364-Cytotoxicity, Immunologic,
pubmed-meshheading:8251364-Fanconi Anemia,
pubmed-meshheading:8251364-Female,
pubmed-meshheading:8251364-Humans,
pubmed-meshheading:8251364-Killer Cells, Natural,
pubmed-meshheading:8251364-Skin Neoplasms,
pubmed-meshheading:8251364-Vulvar Neoplasms
|
| pubmed:year |
1993
|
| pubmed:articleTitle |
Fanconi's anaemia associated with multicentric Bowen's disease and decreased NK cytotoxicity.
|
| pubmed:affiliation |
Service de Dermatologie, Hôpital Saint-Louis, Paris, France.
|
| pubmed:publicationType |
Journal Article,
Case Reports
|