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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1993-12-8
|
| pubmed:abstractText |
Ion-chromatography of lyophilized cobra (Naja naja atra) venom on SP-Sephadex C-50 yielded 14 fractions, of which 7, 8, 9, and 10 possessed neurotoxic actions and 11, 12, 13, and 14 had cytotoxic activities. Chromatography of fraction 14 on SP-Sephadex C-25 gave cytotoxin-14. It was homogeneous on polyacrylamide gel electrophoresis with m = 7448 Da. It was a typical cytotoxin without phospholipase A2 activity and had a selective cytotoxic action on human cancer cell lines.
|
| pubmed:language |
chi
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
0253-9756
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
14
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
279-82
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:8237412-Animals,
pubmed-meshheading:8237412-Antineoplastic Agents,
pubmed-meshheading:8237412-Cobra Venoms,
pubmed-meshheading:8237412-Cytotoxins,
pubmed-meshheading:8237412-Lethal Dose 50,
pubmed-meshheading:8237412-Myocardial Contraction,
pubmed-meshheading:8237412-Rats,
pubmed-meshheading:8237412-Tumor Cells, Cultured
|
| pubmed:year |
1993
|
| pubmed:articleTitle |
[Purification and anticancer activity of cytotoxin-14 from venom of Naja naja atra].
|
| pubmed:affiliation |
Laboratory of Venom Research, Fujian Medical College, Fuzhou, China.
|
| pubmed:publicationType |
Journal Article,
English Abstract
|