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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
22
|
pubmed:dateCreated |
1993-12-1
|
pubmed:abstractText |
Median survival of patients with local-regional gastric carcinoma is 10 months. Resection of the primary tumor and regional lymph nodes, with tumor-free margins (curative resection), has been the most effective treatment for local-regional gastric carcinoma. However, median survival of patients with curative resection of gastric carcinoma is 24 months, and the 5-year survival rate is about 20%. A single institution pilot study has established the feasibility of administering two courses of chemotherapy preoperatively and three courses postoperatively. In another study, a 15% pathologically documented complete response (pathologic complete response) has been reported in unresectable gastric carcinoma treated with etoposide, doxorubicin, and cisplatin.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0027-8874
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
17
|
pubmed:volume |
85
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
1839-44
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8230264-Adenocarcinoma,
pubmed-meshheading:8230264-Adult,
pubmed-meshheading:8230264-Aged,
pubmed-meshheading:8230264-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:8230264-Chemotherapy, Adjuvant,
pubmed-meshheading:8230264-Cisplatin,
pubmed-meshheading:8230264-Doxorubicin,
pubmed-meshheading:8230264-Etoposide,
pubmed-meshheading:8230264-Female,
pubmed-meshheading:8230264-Humans,
pubmed-meshheading:8230264-Male,
pubmed-meshheading:8230264-Middle Aged,
pubmed-meshheading:8230264-Stomach Neoplasms,
pubmed-meshheading:8230264-Survival Analysis,
pubmed-meshheading:8230264-Time Factors,
pubmed-meshheading:8230264-Treatment Failure
|
pubmed:year |
1993
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pubmed:articleTitle |
Preoperative and postoperative combination chemotherapy for potentially resectable gastric carcinoma.
|
pubmed:affiliation |
University of Texas M. D. Anderson Cancer Center, Houston 77030.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study
|