Linked Life Data

8224090

Source:http://linkedlifedata.com/resource/pubmed/id/8224090

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1993-12-10
pubmed:abstractText
Snails from a B. glabrata stock, selected for nonsusceptibility to the NMRI strain of S. mansoni, exhibited unusual schistosome infections, with multiple sporocysts prominent in the head-foot (foot-sporocysts). When F1 progeny from numerous crosses between well-defined susceptible (S) and resistant (R) parental snails were exposed, 60% of the infected snails also exhibited this unusual phenotype. F1 progeny from S x S snail crosses developed normal infections. Foot-sporocysts usually developed much later than secondary sporocysts of normal infections and before 12 weeks postexposure the tissue reaction surrounding foot-sporocysts was less intense than reactions to sporocysts in other tissues of the body. Cercariae were seen emerging directly from foot-sporocysts. Infection of S x R hybrid progeny by three other strains of S. mansoni also resulted in the production of foot-sporocysts. Development of the foot-sporocyst infection phenotype in progeny from many snail crosses suggests that this phenotype is more common than previously recognized. Over 50% of the F1 progeny from S x R parental crosses developed patent infections, a fact relevant to the possible biological control of schistosomiasis by the introduction of refractory snails into endemic areas.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0014-4894
pubmed:author
pubmed:issnType
Print
pubmed:volume
77
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
349-61
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Schistosoma mansoni: analysis of an unusual infection phenotype in the intermediate host snail Biomphalaria glabrata.
pubmed:affiliation
Biomedical Research Institute, Rockville, Maryland 20852.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.