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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
9
|
| pubmed:dateCreated |
1993-12-17
|
| pubmed:abstractText |
The aim of the study was to evaluate the responses to autonomic function tests during the healing period of myocardial infarction (AMI). In 24 patients, at 2 and 6 weeks after the acute event, Valsalva manoeuvre, deep breathing at 6 breaths per min, isometric handgrip and cold pressor tests were performed. Responses of arterial blood pressure (BP) and heart rate (HR) were measured. At 2 weeks post AMI a significant decrease in parasympathetic tone was noted: HR reduction during deep breathing: 18.5 +/- 5.7 beats.min-1 for controls vs 9.7 +/- 2.6 beats.min-1 for AMI, P < 0.001. Systolic BP response to handgrip and cold pressor test was only slightly (non significantly) increased: 30.6 +/- 12.9 mmHg (controls) vs 40.0 +/- 20.5 mmHg (AMI) for the handgrip test and 13.8 +/- 8.1 mmHg vs 18.0 +/- 10.1 mmHg respectively for the cold pressor test. At 6 weeks post AMI, the response to the deep breathing test (15.9 +/- 5.6 beats.min-1) no longer significantly differed from that in controls. In contrast, the sympathetic stressor tests showed a significant increase in systolic BP response: 63.8 +/- 21.9 mmHg, P < 0.001 and 26.1 +/- 14.9 mmHg, P < 0.05, respectively for the handgrip and cold pressor tests. It appeared that infarct localization had no effect on autonomic function tests. There is evidence of autonomic imbalance both at 2 and 6 weeks after AMI, with a rapid but transient decrease in vagal activity and enhancement of orthosympathetic nervous tone; this was markedly more pronounced at 6 weeks post AMI despite treatment with beta-blocking agents in all patients.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Sep
|
| pubmed:issn |
0195-668X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
14
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1189-94
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:8223732-Adult,
pubmed-meshheading:8223732-Autonomic Nervous System,
pubmed-meshheading:8223732-Blood Pressure,
pubmed-meshheading:8223732-Female,
pubmed-meshheading:8223732-Heart Rate,
pubmed-meshheading:8223732-Humans,
pubmed-meshheading:8223732-Male,
pubmed-meshheading:8223732-Middle Aged,
pubmed-meshheading:8223732-Myocardial Infarction,
pubmed-meshheading:8223732-Prospective Studies,
pubmed-meshheading:8223732-Sympathetic Nervous System,
pubmed-meshheading:8223732-Vagus Nerve,
pubmed-meshheading:8223732-Valsalva Maneuver
|
| pubmed:year |
1993
|
| pubmed:articleTitle |
Autonomic imbalance in the recovery period after myocardial infarction.
|
| pubmed:affiliation |
Department of Cardiology, University Hospital, Gent, Belgium.
|
| pubmed:publicationType |
Journal Article
|