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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1994-7-12
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pubmed:abstractText |
To design a rapid and efficient protocol for processing pediatric stool specimens, the authors used 434 specimens to evaluate two commercial latex assays to detect rotavirus (Meritec-Rotavirus and Rotalex) and one to detect adenovirus (Adenolex). Rotavirus latex assay results were compared with electron microscopic examination and adenovirus latex assay results with virus culture. Ninety-two specimens (21%) were positive for rotavirus and 28 (6.5%) for adenovirus; 5 (1%) had both viruses. The sensitivity, specificity, positive predictive values, and negative predictive values for the three assays were, respectively, as follows: Meritec-Rotavirus (97%, 99%, 97%, 99%), Rotalex (91%, 99%, 94%, 98%), and Adenolex (46%, 99%, 77%, 97%). For primary rotavirus screening, the Meritec-Rotavirus and Rotalex latex assays offer a good alternative to electron microscopic examination. For primary adenovirus screening, the low sensitivity of the Adenolex latex assay precludes its use as a routine screen. Its excellent specificity, however, makes it a useful tool for culture confirmation.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0002-9173
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
101
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
742-6
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:8209862-Adenoviridae,
pubmed-meshheading:8209862-Child,
pubmed-meshheading:8209862-Child, Preschool,
pubmed-meshheading:8209862-Drug Costs,
pubmed-meshheading:8209862-Evaluation Studies as Topic,
pubmed-meshheading:8209862-Gastroenteritis,
pubmed-meshheading:8209862-Humans,
pubmed-meshheading:8209862-Infant,
pubmed-meshheading:8209862-Latex Fixation Tests,
pubmed-meshheading:8209862-Reagent Kits, Diagnostic,
pubmed-meshheading:8209862-Rotavirus,
pubmed-meshheading:8209862-Sensitivity and Specificity,
pubmed-meshheading:8209862-Virus Diseases
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pubmed:year |
1994
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pubmed:articleTitle |
The utility of latex agglutination assays in the diagnosis of pediatric viral gastroenteritis.
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pubmed:affiliation |
Department of Pathology, University of British Columbia, Vancouver, Canada.
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pubmed:publicationType |
Journal Article
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