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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1994-7-5
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pubmed:abstractText |
Several studies have now demonstrated that low serum albumin and/or low protein catabolic rates correlate with increased risk of death in the chronic hemodialysis patient. A study involving 81 patients receiving thrice-weekly hemodialysis treatments and who had either a low serum albumin and/or protein catabolic rate was conducted to compare the effect of intradialytic parenteral nutrition (IDPN) on mortality rates. Fifty patients received IDPN and 31 patients did not. Thirty-eight of the patients were black (47%), 34 were white (42%), and 9 were Hispanic (11%). The study included 33 diabetic patients (41%), 20 of whom received IDPN. Nondiabetic patients received an average of 725 kcal/hemodialysis treatment and diabetic patients received an average of 670 kcal/hemodialysis treatment. The average length of treatment was 9 months. The results of the study revealed a better survival rate (64% v 52%) for patients treated with IDPN. Using Cox analysis, the IDPN-treated group had a significantly better survival rate (P < 0.01). Serum albumin increased by 12% in the survivors. There was no difference in survival when considered separately for diabetic and nondiabetic patients who received IDPN (mortality rate for diabetics: 50% for treated patients and 54% for untreated patients; mortality rate for nondiabetics: 26% for treated patients and 44% for untreated patients). However, the nondiabetic treated patients had the lowest mortality rates. In conclusion, correction of hypoalbuminemia by IDPN significantly reduced mortality rates overall.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0272-6386
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
808-16
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8203363-Body Weight,
pubmed-meshheading:8203363-Diabetic Nephropathies,
pubmed-meshheading:8203363-Female,
pubmed-meshheading:8203363-Humans,
pubmed-meshheading:8203363-Kidney Failure, Chronic,
pubmed-meshheading:8203363-Male,
pubmed-meshheading:8203363-Middle Aged,
pubmed-meshheading:8203363-Parenteral Nutrition,
pubmed-meshheading:8203363-Renal Dialysis,
pubmed-meshheading:8203363-Retrospective Studies,
pubmed-meshheading:8203363-Serum Albumin,
pubmed-meshheading:8203363-Survival Rate,
pubmed-meshheading:8203363-Urea
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pubmed:year |
1994
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pubmed:articleTitle |
Effect of intradialytic parenteral nutrition on mortality rates in end-stage renal disease care.
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pubmed:affiliation |
Department of Medicine, Our Lady of Lourdes Medical Center, Camden, NJ 08103.
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pubmed:publicationType |
Journal Article
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