Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1976-9-2
pubmed:abstractText
Almost all the chromatin in nuclei of regenerating rat liver hepatocytes 15 h and particularly 24 h after partial hepatectomy appeared as decondensed chromatin. Treatment with alpha-amanitine induced a clear condensation of decondensed chromatin as early as 30 min after toxin injection. The degree of condensation increased further until, 2 h after poisoning, almost all the chromatin was found to be in condensed form. Because the synthesis of DNA, after toxin injection, was not modified during the first 2h and 30 min, our results indicate that the chromatin condensation did not affect the synthesis of DNA. In the present paper the relationships between the inhibition of RNA synthesis and the chromatin ultrastructural changes are also discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0340-6075
pubmed:author
pubmed:issnType
Print
pubmed:day
26
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
307-18
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Effects of alpha-amanitine on chromatin in regenerating rat hepatocytes: a biochemical and morphologic study.
pubmed:publicationType
Journal Article