rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
1
|
pubmed:dateCreated |
1994-7-6
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pubmed:databankReference |
|
pubmed:abstractText |
Sequence analysis of a 5753-bp genomic fragment of Rhodococcus sp. NI86/21 revealed the presence of three homologues of known cobalamin biosynthetic genes. One of these genes encodes a protein showing strong homology with the precorrin-6x reductase (CobK) of Pseudomonas denitrificans. In addition, the rhodococcal homologue of the corrin methyltransferases, CobM from P. denitrificans and CbiF from Salmonella typhimurium, was identified. The protein deduced from a third Rhodococcus gene aligns well with CobL of P. denitrificans and with the protein pair CbiE/CbiT of S. typhimurium, which are involved in corrin methylation and decarboxylation.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0378-1119
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
27
|
pubmed:volume |
143
|
pubmed:geneSymbol |
cbiE,
cbiF,
cbiT,
cobK,
cobL,
cobM
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
91-3
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:8200543-Amino Acid Sequence,
pubmed-meshheading:8200543-Bacterial Proteins,
pubmed-meshheading:8200543-Genes, Bacterial,
pubmed-meshheading:8200543-Methyltransferases,
pubmed-meshheading:8200543-Molecular Sequence Data,
pubmed-meshheading:8200543-Multigene Family,
pubmed-meshheading:8200543-Oxidoreductases,
pubmed-meshheading:8200543-Pseudomonas,
pubmed-meshheading:8200543-Rhodococcus,
pubmed-meshheading:8200543-Salmonella typhimurium,
pubmed-meshheading:8200543-Sequence Alignment,
pubmed-meshheading:8200543-Sequence Homology, Amino Acid,
pubmed-meshheading:8200543-Vitamin B 12
|
pubmed:year |
1994
|
pubmed:articleTitle |
Sequences of the cobalamin biosynthetic genes cobK, cobL and cobM from Rhodococcus sp. NI86/21.
|
pubmed:affiliation |
F.A. Janssens Laboratory of Genetics, Catholic University of Leuven, Heverlee, Belgium.
|
pubmed:publicationType |
Journal Article,
Comparative Study
|