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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1994-6-29
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pubmed:abstractText |
A 28 kDa-protein with inhibitory activity on collagen- and ADP-induced platelet aggregation was purified from the venom of the snake Bothrops jararaca. Its complete amino acid sequence corresponded to the carboxyl-terminal region consisting of disintegrin-like and cysteine-rich domains of jararhagin, a high molecular weight hemorrhagic metalloprotease. Sequence homology of the protein to other disintegrins and disintegrin-like proteins from various snake venoms is also presented.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0006-291X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
30
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pubmed:volume |
201
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
331-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8198592-Adenosine Diphosphate,
pubmed-meshheading:8198592-Amino Acid Sequence,
pubmed-meshheading:8198592-Collagen,
pubmed-meshheading:8198592-Crotalid Venoms,
pubmed-meshheading:8198592-Humans,
pubmed-meshheading:8198592-Metalloendopeptidases,
pubmed-meshheading:8198592-Molecular Sequence Data,
pubmed-meshheading:8198592-Molecular Weight,
pubmed-meshheading:8198592-Peptide Fragments,
pubmed-meshheading:8198592-Platelet Aggregation,
pubmed-meshheading:8198592-Platelet Aggregation Inhibitors,
pubmed-meshheading:8198592-Sequence Alignment,
pubmed-meshheading:8198592-Sequence Homology, Amino Acid
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pubmed:year |
1994
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pubmed:articleTitle |
A 28 kDa-protein with disintegrin-like structure (jararhagin-C) purified from Bothrops jararaca venom inhibits collagen- and ADP-induced platelet aggregation.
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pubmed:affiliation |
Department of Pharmaceutics, Gifu Pharmaceutical University, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study,
In Vitro,
Research Support, Non-U.S. Gov't
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