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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1994-6-27
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pubmed:abstractText |
Five weeks after a four-day visit to Malta, a 39-year old white male German national developed septic temperatures of up to 40 degrees C, progressive jaundice and a pronounced hepatosplenomegaly. The initial examination showed a very sick, somnolent patient with jaundice, cyanosis, tachypnea and a markedly enlarged liver on both physical examination and sonography. The laboratory evaluation revealed a moderate leukocytosis, markedly accelerated ESR, poor liver function with strongly elevated gamma-GT and alkaline phosphatase levels. Primary antibiotic therapy consisted of doxycycline. Ultrasound examination of the liver four days after admission revealed multiple hypodense abscesses. On the sixth day after admission, gram-negative rods were first isolated from blood cultures; antibiotic therapy was switched to ofloxacin (2 x 400 mg/day) and amoxycillin (3 x 2 g/day) after sensitivity testing. As a result of treatment with this combination of antibiotics, the patient was free of fever 10 days after hospitalization; on the same day yersinia enterocolitica was isolated from the first blood cultures taken on admission. The diagnosis of non-enteric forms of yersinia infection can prove very difficult, especially if the serology is not clear cut and there are no immunological complications. A presentation including intermittent fever, moderate leukocytosis, strongly accelerated ESR and multiple hypodense abscesses in the liver should lead one to consider a non-enteric type of yersinia infection. Hepatic abscesses usually occur in patients who have an iron overload.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0044-2771
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
32
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
152-6
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:8197810-Adult,
pubmed-meshheading:8197810-Anti-Bacterial Agents,
pubmed-meshheading:8197810-Bacteriological Techniques,
pubmed-meshheading:8197810-Diagnosis, Differential,
pubmed-meshheading:8197810-Drug Therapy, Combination,
pubmed-meshheading:8197810-Humans,
pubmed-meshheading:8197810-Liver Abscess,
pubmed-meshheading:8197810-Liver Cirrhosis, Alcoholic,
pubmed-meshheading:8197810-Liver Function Tests,
pubmed-meshheading:8197810-Male,
pubmed-meshheading:8197810-Malta,
pubmed-meshheading:8197810-Sepsis,
pubmed-meshheading:8197810-Travel,
pubmed-meshheading:8197810-Yersinia Infections,
pubmed-meshheading:8197810-Yersinia enterocolitica
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pubmed:year |
1994
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pubmed:articleTitle |
[Yersinia enterocolitica infection with extraintestinal manifestations: case report and overview].
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pubmed:affiliation |
Abteilung Innere Medizin, PIUS-Hospital Oldenburg.
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pubmed:publicationType |
Journal Article,
English Abstract,
Review,
Case Reports
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