Linked Life Data

8194902

Source:http://linkedlifedata.com/resource/pubmed/id/8194902

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1994-6-27
pubmed:abstractText
We reacted the Third International IASLC Workshop panel of monoclonal antibodies (MAbs) directed against human lung-tumor-associated epitopes with nitrocellulose blots of total proteins from adult fruit flies. Out of 63 MAbs tested, 9 showed a significant reaction with Drosophila proteins. Interestingly, in a double-blind analysis, most of the positive reactions fell into clusters that parallel the antibody reactivities against human tissues. In light of our findings, it becomes possible to screen expression vector libraries in order to isolate Drosophila cDNA that may have homology with human tumor-associated antigens.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0898-6924
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
96-7
pubmed:dateRevised
2007-7-23
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Monoclonal antibodies directed against human tumor-associated antigens cross-react with Drosophila proteins in clusters.
pubmed:affiliation
Department of Pharmacological and Physiological Sciences, University of Chicago, IL 60637.
pubmed:publicationType
Journal Article, Comparative Study