Linked Life Data

8192718

Source:http://linkedlifedata.com/resource/pubmed/id/8192718

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1993-5-20
pubmed:abstractText
A comparison between different caramels described for use in the pharmaceutical industry is presented. An interfering substance, 5-hydroxymethylfurfural (5-HMF), was detected in some caramels. Conditions and proofs for the formation of 5-HMF are presented. Interference by 5-HMF during the analysis of the active drugs and the possibility of interaction with the active drugs during the shelf-life of the drug formulation are discussed. A limit test for 5-HMF in caramel was developed. The test depends on measuring the difference in absorbance between two equimolar solutions of caramel, one of which contains sodium borohydride. The test is sensitive and selective for the detection and determination of trace amounts of 5-HMF without interference from the brown products of caramel.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0269-4727
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
49-53
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Detection and determination of interfering 5-hydroxymethylfurfural in the analysis of caramel-coloured pharmaceutical syrups.
pubmed:affiliation
Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, University of Alexandria, Egypt.
pubmed:publicationType
Journal Article, Comparative Study