Linked Life Data

8184004

Source:http://linkedlifedata.com/resource/pubmed/id/8184004

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1994-6-14
pubmed:abstractText
The radiation-induced "in-pulse" luminescence emission from solid DNA containing either metronidazole or a highly electron-affinic 5-nitrofuran in the range 3-2000 (w:w) base pairs per additive molecule has been investigated in vacuo at 293 K using electron pulses of energy below 260 keV. The luminescence intensity at 450 nm from DNA decreases with increasing content of the additive in the sample and approaches a limiting level at high concentrations of the additives. At these higher concentrations the limiting value represents about 50% of that observed from DNA alone. It is shown that the efficiency of the additives in reducing the luminescence intensity is dependent upon their redox potential E1(7); this dependence is consistent with these additives acting as electron acceptors. It is concluded that the ability of the electron acceptors to reduce the luminescence is related to the electron affinity of E1(7) of the acceptors and electron migration distances of at least 300 base pairs are proposed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0033-7587
pubmed:author
pubmed:issnType
Print
pubmed:volume
138
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
307-11
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Radiation-induced luminescence in DNA: evidence for long-range electron migration.
pubmed:affiliation
MRC Radiobiology Unit, Didcot, Oxon, United Kingdom.
pubmed:publicationType
Journal Article