rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1994-6-14
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pubmed:abstractText |
We have recently shown that angiotensin II-induced hypertrophy of cultured rat cardiomyocytes was partially blocked by an endothelin (ET) receptor antagonist (BQ123) selective for the ETA subtype, suggesting the possible involvement of endogenous ET-1 in the mechanism of cardiac hypertrophy in vitro. In the present study, we studied the in vivo blockade effects of BQ123 on cardiac hypertrophy provoked by left ventricular overload with aortic banding in adult rats.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Actins,
http://linkedlifedata.com/resource/pubmed/chemical/Atrial Natriuretic Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Endothelin-1,
http://linkedlifedata.com/resource/pubmed/chemical/Endothelins,
http://linkedlifedata.com/resource/pubmed/chemical/Peptides, Cyclic,
http://linkedlifedata.com/resource/pubmed/chemical/Protein Precursors,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Endothelin,
http://linkedlifedata.com/resource/pubmed/chemical/cyclo(Trp-Asp-Pro-Val-Leu)
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0009-7322
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
89
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2198-203
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8181145-Actins,
pubmed-meshheading:8181145-Animals,
pubmed-meshheading:8181145-Atrial Natriuretic Factor,
pubmed-meshheading:8181145-Endothelin-1,
pubmed-meshheading:8181145-Endothelins,
pubmed-meshheading:8181145-Gene Expression,
pubmed-meshheading:8181145-Hypertrophy, Left Ventricular,
pubmed-meshheading:8181145-Male,
pubmed-meshheading:8181145-Peptides, Cyclic,
pubmed-meshheading:8181145-Protein Precursors,
pubmed-meshheading:8181145-RNA, Messenger,
pubmed-meshheading:8181145-Rats,
pubmed-meshheading:8181145-Rats, Wistar,
pubmed-meshheading:8181145-Receptors, Endothelin
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pubmed:year |
1994
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pubmed:articleTitle |
Endothelin ETA receptor antagonist blocks cardiac hypertrophy provoked by hemodynamic overload.
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pubmed:affiliation |
Second Department of Internal Medicine, Tokyo Medical and Dental University, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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