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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1994-5-10
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pubmed:abstractText |
The present study examines the role of host genetics in predisposition to Ascaris lumbricoides and Trichuris trichiura infection, by comparing the associations between age-standardized infection intensities of parents and their children (genetically related), with age-standardized infection intensities of parents alone (not related), within families previously demonstrated to exhibit familial predisposition. The lack of a consistent trend in infection intensity associations within families, in particular the lack of a stronger association between parents and their children than between unrelated parents, suggests that host genetic factors are not a major determinant of infection status. If there is a genetic basis for predisposition, then the data suggest that the effects of this genetic basis are overwhelmed by other, environmental or behavioural features of the family household.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0031-1820
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
108 ( Pt 1)
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
77-80
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pubmed:dateRevised |
2009-9-29
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pubmed:meshHeading |
pubmed-meshheading:8152858-Adolescent,
pubmed-meshheading:8152858-Adult,
pubmed-meshheading:8152858-Animals,
pubmed-meshheading:8152858-Ascariasis,
pubmed-meshheading:8152858-Ascaris lumbricoides,
pubmed-meshheading:8152858-Child,
pubmed-meshheading:8152858-Child, Preschool,
pubmed-meshheading:8152858-Feces,
pubmed-meshheading:8152858-Female,
pubmed-meshheading:8152858-Genetic Predisposition to Disease,
pubmed-meshheading:8152858-Humans,
pubmed-meshheading:8152858-Male,
pubmed-meshheading:8152858-Parasite Egg Count,
pubmed-meshheading:8152858-Trichuriasis
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pubmed:year |
1994
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pubmed:articleTitle |
Genetic relatedness as a determinant of predisposition to Ascaris lumbricoides and Trichuris trichiura infection.
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pubmed:affiliation |
Department of Biology, Imperial College, London, U.K.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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