Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1994-5-11
pubmed:abstractText
Tissues of adult rabbit brain were shown to enzymatically oxidize retinol and retinaldehyde to retinoic acid, a potent stimulator of gene expression. Rates of retinoic acid synthesis by the cerebrum, cerebellum, and meninges were comparable to, or exceeded, rates measured with rat liver, an organ known to have a relatively high capacity to synthesize retinoic acid. These results, taken together with previous observations that the adult brain contains retinoic acid-activated transcription factors and cellular retinoid-binding proteins, suggest that retinoids may play an important role in the adult central nervous system.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
31
pubmed:volume
632
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
325-8
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Adult rabbit brain synthesizes retinoic acid.
pubmed:affiliation
Department of Ophthalmology L-907, Boston University School of Medicine, MA 02118.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't