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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1994-5-4
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pubmed:abstractText |
Effects of cis and trans monounsaturated fatty acids (TFA) and saturated fatty acids were assessed in 29 men and 29 women consuming controlled diets. Subjects ate each diet for 6 wk in a Latin square design. The diets, each with 39-40% of energy as fat were: 1) high oleic (16.7% of energy as oleic acid), 2) moderate TFA (3.8% of energy as TFA), 3) high TFA (6.6% of energy as TFA), 4) and saturated (16.2% of energy as lauric+myristic+palmitic acids). Compared with the oleic diet, LDL cholesterol increased 6.0%, 7.8%, and 9.0% after moderate TFA, high TFA, and saturated diets, respectively. HDL cholesterol was unchanged after moderate TFA, but was slightly lower (2.8%) after high TFA. HDL cholesterol after the saturated diet was 3.5% higher than after the oleic diet. Changes in apolipoproteins B and A-I corresponded with changes in the lipoprotein cholesterols. Thus, compared with oleic acid, dietary TFAs raise LDL cholesterol, but to a slightly lesser degree than do saturates, and high TFA concentrations may result in minor reductions of HDL cholesterol.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Apolipoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol,
http://linkedlifedata.com/resource/pubmed/chemical/Dietary Fats,
http://linkedlifedata.com/resource/pubmed/chemical/Fatty Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Fatty Acids, Monounsaturated,
http://linkedlifedata.com/resource/pubmed/chemical/Lipids,
http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Triglycerides
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0002-9165
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
59
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
861-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8147331-Adult,
pubmed-meshheading:8147331-Aged,
pubmed-meshheading:8147331-Apolipoproteins,
pubmed-meshheading:8147331-Cholesterol,
pubmed-meshheading:8147331-Dietary Fats,
pubmed-meshheading:8147331-Fatty Acids,
pubmed-meshheading:8147331-Fatty Acids, Monounsaturated,
pubmed-meshheading:8147331-Female,
pubmed-meshheading:8147331-Humans,
pubmed-meshheading:8147331-Lipids,
pubmed-meshheading:8147331-Lipoproteins,
pubmed-meshheading:8147331-Male,
pubmed-meshheading:8147331-Middle Aged,
pubmed-meshheading:8147331-Sex Factors,
pubmed-meshheading:8147331-Stereoisomerism,
pubmed-meshheading:8147331-Triglycerides
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pubmed:year |
1994
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pubmed:articleTitle |
Dietary trans fatty acids: effects on plasma lipids and lipoproteins of healthy men and women.
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pubmed:affiliation |
Lipid Nutrition Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, US Department of Agriculture, MD.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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