Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1994-5-4
|
pubmed:abstractText |
The efficacy of ketoprofen in the treatment of acute clinical mastitis was evaluated in a clinical trial comprising a non-blind controlled study and a blind, placebo-controlled study. All the cows were treated with 20 g sulphadiazine and 4 g trimethoprim intramuscularly upon diagnosis, and half the dosage was given once daily thereafter. In addition, the ketoprofen treatment groups received 2 g ketoprofen intramuscularly once daily for the duration of the antimicrobial therapy. Recovery rates for the non-blind contemporary controls and the blind placebo-controls were 83.7 per cent and 70.7 per cent, respectively. In the non-blind controlled ketoprofen and the placebo-controlled ketoprofen treatment groups, recovery rates were 94.7 per cent and 92.3 per cent, respectively. The odds ratio (OR) of recovery was significantly (P < or = 0.01) high in the placebo-controlled study (OR = 6.75, confidence interval [CI] = 1.45 to 31.4), and high but not significant in the non-blind controlled study (OR = 2.64, CI = 0.53 to 13.10). It was concluded that ketoprofen significantly improved recovery in clinical mastitis in dairy cows.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Drug Combinations,
http://linkedlifedata.com/resource/pubmed/chemical/Ketoprofen,
http://linkedlifedata.com/resource/pubmed/chemical/Sulfadiazine,
http://linkedlifedata.com/resource/pubmed/chemical/Trimethoprim,
http://linkedlifedata.com/resource/pubmed/chemical/sulfadiazine, trimethoprim drug...
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
0034-5288
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
56
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
62-8
|
pubmed:dateRevised |
2010-11-10
|
pubmed:meshHeading |
pubmed-meshheading:8146455-Animals,
pubmed-meshheading:8146455-Cattle,
pubmed-meshheading:8146455-Drug Combinations,
pubmed-meshheading:8146455-Female,
pubmed-meshheading:8146455-Ketoprofen,
pubmed-meshheading:8146455-Mastitis, Bovine,
pubmed-meshheading:8146455-Single-Blind Method,
pubmed-meshheading:8146455-Sulfadiazine,
pubmed-meshheading:8146455-Trimethoprim
|
pubmed:year |
1994
|
pubmed:articleTitle |
Anti-inflammatory ketoprofen in the treatment of field cases of bovine mastitis.
|
pubmed:affiliation |
Hachaklait Veterinary Services, Hebrew University of Jerusalem, Israel.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
|