Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1994-4-25
|
| pubmed:abstractText |
The relation between contraceptive methods and risk of pelvic endometriosis has been analyzed in a case-control study. Cases were 376 women with laparoscopically or laparotomically confirmed pelvic endometriosis admitted to a network of Obstetrics and Gynecology Clinics in Lombardy, Northern Italy. Controls were 522 women admitted for acute non-gynecological and non-obstetrics conditions to the same hospitals where cases had been identified. A total 153 women (40.3%) out of the 377 cases and 154 (29.7%) out of the 522 controls reported ever oral contraceptive (OC) use: the corresponding relative risk (RR) was 1.6 (95% confidence interval, CI, 1.2-2.2). The risk was restricted to ex-OC users (RR 1.7, 95% CI 1.3-2.4), the estimated RR for current users being 0.9 (95% CI 0.5-1.9). No clear relation emerged with duration, recency and latency of OC use and risk of endometriosis. In comparison with never IUD users, the risk for ever users was 1.3 (95% CI 0.6-2.8), and no clear relation emerged with duration of use. Likewise, no association was observed between barrier method of contraception and risk of endometriosis (RR ever vs never users 0.5, 95% CI 0.3-1.4). The role of selection and other biases should be considered in the interpretation of epidemiological data on the role of OC on the risk of endometriosis.
|
| pubmed:keyword |
http://linkedlifedata.com/resource/pubmed/keyword/Barrier Methods,
http://linkedlifedata.com/resource/pubmed/keyword/Bias,
http://linkedlifedata.com/resource/pubmed/keyword/Biology,
http://linkedlifedata.com/resource/pubmed/keyword/Case Control Studies,
http://linkedlifedata.com/resource/pubmed/keyword/Contraception,
http://linkedlifedata.com/resource/pubmed/keyword/Contraceptive Methods,
http://linkedlifedata.com/resource/pubmed/keyword/Developed Countries,
http://linkedlifedata.com/resource/pubmed/keyword/Endometrial Effects,
http://linkedlifedata.com/resource/pubmed/keyword/Endometrium,
http://linkedlifedata.com/resource/pubmed/keyword/Error Sources,
http://linkedlifedata.com/resource/pubmed/keyword/Europe,
http://linkedlifedata.com/resource/pubmed/keyword/Family Planning,
http://linkedlifedata.com/resource/pubmed/keyword/Genitalia,
http://linkedlifedata.com/resource/pubmed/keyword/Genitalia, Female,
http://linkedlifedata.com/resource/pubmed/keyword/ITALY,
http://linkedlifedata.com/resource/pubmed/keyword/Iud,
http://linkedlifedata.com/resource/pubmed/keyword/Measurement,
http://linkedlifedata.com/resource/pubmed/keyword/Mediterranean Countries,
http://linkedlifedata.com/resource/pubmed/keyword/Oral Contraceptives,
http://linkedlifedata.com/resource/pubmed/keyword/Physiology,
http://linkedlifedata.com/resource/pubmed/keyword/Risk Factors,
http://linkedlifedata.com/resource/pubmed/keyword/Southern Europe,
http://linkedlifedata.com/resource/pubmed/keyword/Studies,
http://linkedlifedata.com/resource/pubmed/keyword/Technical Report,
http://linkedlifedata.com/resource/pubmed/keyword/Urogenital System,
http://linkedlifedata.com/resource/pubmed/keyword/Uterus
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
0010-7824
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
49
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
47-55
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:otherAbstract |
PIP: In northern Italy, physicians compared data on 376 women with laparoscopically or laparotomically confirmed pelvic endometriosis with data on 522 age-matched controls admitted for acute nongynecologic and nonobstetric conditions to the same hospitals to examine the association between contraceptive methods and pelvic endometriosis. Cases were more likely to have ever used oral contraceptives (OCs) than controls (40.3% vs. 29.7%; relative risk [RR] = 1.6), but the risk was limited to former OC users (RR = 1.7 vs. 0.9 for current users). There was no clear association with duration, recency and latency of OC use and risk of endometriosis. The relative risk of endometriosis for ever users of the IUD was 1.3. Duration of IUD use was not associated with endometriosis risk. Use of barrier methods was not correlated with risk of endometriosis (RR = 0.5). Before making any conclusions on the association between use of contraceptive methods and pelvic endometriosis, one should consider possible selection and other biases when interpreting epidemiologic data. For example, painful menstruation is a common symptom of endometriosis and a major indication for OC use. Thus, women with endometriosis-induced dysmenorrhea tend to be ever OC users.
|
| pubmed:meshHeading |
pubmed-meshheading:8137625-Adult,
pubmed-meshheading:8137625-Case-Control Studies,
pubmed-meshheading:8137625-Contraceptives, Oral,
pubmed-meshheading:8137625-Endometriosis,
pubmed-meshheading:8137625-Female,
pubmed-meshheading:8137625-Humans,
pubmed-meshheading:8137625-Intrauterine Devices,
pubmed-meshheading:8137625-Risk Factors
|
| pubmed:year |
1994
|
| pubmed:articleTitle |
Contraceptive methods and risk of pelvic endometriosis.
|
| pubmed:affiliation |
Istituto di Richerche Farmacologiche Mario Negri, Milano, Italy.
|
| pubmed:publicationType |
Journal Article,
Comparative Study
|