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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3-4
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pubmed:dateCreated |
1994-4-19
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pubmed:abstractText |
We studied the effect of Kami-kihi-to (Jia-Wei-Gui-Pi-Tang) on the production of autoantibodies in ten patients with chronic immune thrombocytopenic purpura. After administration of Kami-kihi-to, platelet count was increased in seven of the ten patients (p < 0.05). Using Western blotting, we demonstrated the disappearance of autoantibody reaction with antigen in one patient. However, platelet-associated IgG was decreased in eight of ten patients (p < 0.05). Kami-kihi-to appears to promote the suppression of autoantibodies in patients with chronic immune thrombocytopenic purpura. No side effects were observed in any patient. Thus, Kami-kihi-to may be a useful and safe drug in the management of chronic immune thrombocytopenia purpura.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0192-415X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
251-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8135169-Administration, Oral,
pubmed-meshheading:8135169-Adult,
pubmed-meshheading:8135169-Aged,
pubmed-meshheading:8135169-Autoantibodies,
pubmed-meshheading:8135169-Blood Platelets,
pubmed-meshheading:8135169-Blotting, Western,
pubmed-meshheading:8135169-Drugs, Chinese Herbal,
pubmed-meshheading:8135169-Female,
pubmed-meshheading:8135169-Humans,
pubmed-meshheading:8135169-Immunoglobulin G,
pubmed-meshheading:8135169-Male,
pubmed-meshheading:8135169-Middle Aged,
pubmed-meshheading:8135169-Platelet Count,
pubmed-meshheading:8135169-Purpura, Thrombocytopenic, Idiopathic
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pubmed:year |
1993
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pubmed:articleTitle |
Effects of kami-kihi-to (jia-wei-gui-pi-tang) on autoantibodies in patients with chronic immune thrombocytopenic purpura.
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pubmed:affiliation |
First Department of Internal Medicine, Kansai Medical University, Osaka, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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