Linked Life Data

8130527

Source:http://linkedlifedata.com/resource/pubmed/id/8130527

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1994-4-21
pubmed:abstractText
Pharmacoinformatics is the area of Medical Informatics concerned with modeling and simulation of the behavior of drugs, and control of such behavior by individualized dosage regimens for each patient to achieve explicitly chosen therapeutic goals. The credibility of serum concentration data is a major factor in such modeling. The present report examines a more precise way of describing the credibility of such data with a collection of polynomial equations, developed from routine survey data of the College of American Pathologists, which improve the description of the credibility of serum level results when compared to the usual practice of describing the assay coefficient of variation in the usual manner and then not using such information either in population pharmacokinetic modeling or in actual therapeutic drug monitoring. These equations can be used until each laboratory can develop its own assay error patterns with its own similar polynomial equations.
pubmed:grant
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0195-4210
pubmed:author
pubmed:issnType
Print
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
517-21
pubmed:dateRevised
2010-9-10
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Pharmacoinformatics: equations for serum drug assay error patterns; implications for therapeutic drug monitoring and dosage.
pubmed:affiliation
Laboratory of Applied Pharmacokinetics, University of Southern California School of Medicine, Los Angeles 90033.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't