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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1994-4-11
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pubmed:abstractText |
Adult dairy cows were treated with a range of doses (0.0125mg to 0.4mg) of synthetic ACTH1-24 and the plasma cortisol response was measured. Peak response was independent of dose. Higher doses of ACTH had a more prolonged effect such that the integrated response was dose dependent. Dose response curves were examined by regression analyses. Individual cows had a significant effect on y-axis intercept but not on the slope of the regression lines examined. A dose rate of 0.05mg ACTH iv was identified as a suitable dose rate for use in clinical assessment of adrenal cortex function, with 0, 50 and 120 min following ACTH being critical sampling times to identify the response.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0739-7240
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
115-23
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8124927-Adrenal Cortex,
pubmed-meshheading:8124927-Adrenocorticotropic Hormone,
pubmed-meshheading:8124927-Animals,
pubmed-meshheading:8124927-Cattle,
pubmed-meshheading:8124927-Dose-Response Relationship, Drug,
pubmed-meshheading:8124927-Female,
pubmed-meshheading:8124927-Hydrocortisone
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pubmed:year |
1994
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pubmed:articleTitle |
Adrenal cortex response to adrenocorticotropic hormone in dairy cattle.
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pubmed:affiliation |
Dairying Research Corporation, Hamilton, New Zealand.
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pubmed:publicationType |
Journal Article
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