Linked Life Data

8123040

Source:http://linkedlifedata.com/resource/pubmed/id/8123040

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1994-4-1
pubmed:abstractText
A novel ribosome-inactivating protein designated beta-kirilowin was isolated from the seeds of Trichosanthes kirilowii. The proteins exhibited strong abortifacient activity in pregnant mice and produced a single band after SDS-polyacrylamide gel electrophoresis with an apparent mol. wt. of 27,500 daltons. It was active in inhibiting the cell-free translation system with an ID50 of about 1.8 ng/ml. No cross-reactivity with trichosanthin could be detected by immunodiffusion. Sequence comparison of the first 10 residues of beta-kirilowin with ribosome-inactivating proteins isolated from T. kirilowii such as trichosanthin, trichokirin and karasurin indicated 70%, 60% and 70% identity, respectively.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0006-291X
pubmed:author
pubmed:issnType
Print
pubmed:day
28
pubmed:volume
199
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
387-93
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Isolation and characterization of a novel ribosome-inactivating protein, beta-kirilowin, from the seeds of Trichosanthes kirilowii.
pubmed:affiliation
Department of Biochemistry, Chinese University of Hong Kong, Shiantin, New Territories.
pubmed:publicationType
Journal Article, Comparative Study