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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1993-5-20
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pubmed:abstractText |
Recipients (4076) and donors (3325) of kidney transplants performed at 110 transplant centers were typed for HLA-DRB by the DNA RFLP method. The discrepancy rate of replicate samples distributed among 8 participating laboratories was a low 2.6%. The discrepancy rate between RFLP-DRB and serological HLA-DR typings was 25.0% for organ donors and 27.6% for kidney recipients. Discrepancy rates at the different transplant centers ranged from 9.7% to 86.7%. The discrepancies consisted of antigens being incorrectly interpreted by serology (16.8%), and of serological "blanks" turning out to be definable alleles by the DNA method (10.8%). The alleles that were mainly affected by discrepancies were DR1, DR8, DR10, DR12, DR13, DR14, DR16, DR17.2, and DR18.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0041-1337
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
55
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
778-81
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8097342-Alleles,
pubmed-meshheading:8097342-DNA,
pubmed-meshheading:8097342-HLA-DR Antigens,
pubmed-meshheading:8097342-Histocompatibility Testing,
pubmed-meshheading:8097342-Homozygote,
pubmed-meshheading:8097342-Humans,
pubmed-meshheading:8097342-Kidney Transplantation,
pubmed-meshheading:8097342-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:8097342-Quality Control
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pubmed:year |
1993
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pubmed:articleTitle |
DNA HLA-DR typing results of 4000 kidney transplants.
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pubmed:affiliation |
Transplant Laboratory, University of Heidelberg, Germany.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Multicenter Study
|