| pubmed-article:8080930 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8080930 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:8080930 | lifeskim:mentions | umls-concept:C0220825 | lld:lifeskim |
| pubmed-article:8080930 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:8080930 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
| pubmed-article:8080930 | lifeskim:mentions | umls-concept:C2348480 | lld:lifeskim |
| pubmed-article:8080930 | lifeskim:mentions | umls-concept:C0137758 | lld:lifeskim |
| pubmed-article:8080930 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:8080930 | pubmed:dateCreated | 1994-10-11 | lld:pubmed |
| pubmed-article:8080930 | pubmed:abstractText | A series of segmented polydimethylsiloxane (PDMS) polyurea-urethanes was synthesized based on hexane diisocyanate modified polyether-PDMS soft segments. The hard segments consisted of 4,4'-methylene diphenylene diisocyanate, which was chain extended with 1,4-butanediol. The effect of chemical composition of the polyether-PDMS soft segments on the extent of phase separation, physical properties and surface properties was studied using a variety of techniques including dynamic mechanical analysis, tensile testing, X-ray photoelectron spectroscopy (XPS) and contact angle analysis. The polymers were also evaluated for their blood-contacting properties in a canine ex vivo model. The PDMS polyurea-urethanes containing polyether-PDMS soft segments showed three distinct phases: a PDMS-rich phase, a polyol soft segment-rich phase and a hard segment-rich phase. The tensile strength and modulus of these materials were not significantly lower compared to a polymer without PDMS in the soft segment. XPS revealed the surface enrichment of the hydrophobic PDMS component at the air-solid interface. Dynamic contact angle measurements indicated that the PDMS-based polyurea-urethanes possessed a hydrophobic surface in water. The PDMS polyurea-urethanes showed lower adherent platelet and fibrinogen deposition compared to a polymer without PDMS in the soft segment. Varying the amount of PDMS in the soft segment of these polymers did not reveal significant differences in their blood-contacting properties. | lld:pubmed |
| pubmed-article:8080930 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8080930 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8080930 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8080930 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8080930 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8080930 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8080930 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8080930 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8080930 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8080930 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8080930 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8080930 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8080930 | pubmed:month | May | lld:pubmed |
| pubmed-article:8080930 | pubmed:issn | 0142-9612 | lld:pubmed |
| pubmed-article:8080930 | pubmed:author | pubmed-author:CooperS LSL | lld:pubmed |
| pubmed-article:8080930 | pubmed:author | pubmed-author:LiuNN | lld:pubmed |
| pubmed-article:8080930 | pubmed:author | pubmed-author:YangC ZCZ | lld:pubmed |
| pubmed-article:8080930 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8080930 | pubmed:volume | 15 | lld:pubmed |
| pubmed-article:8080930 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8080930 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8080930 | pubmed:pagination | 408-16 | lld:pubmed |
| pubmed-article:8080930 | pubmed:dateRevised | 2009-2-7 | lld:pubmed |
| pubmed-article:8080930 | pubmed:meshHeading | pubmed-meshheading:8080930-... | lld:pubmed |
| pubmed-article:8080930 | pubmed:meshHeading | pubmed-meshheading:8080930-... | lld:pubmed |
| pubmed-article:8080930 | pubmed:meshHeading | pubmed-meshheading:8080930-... | lld:pubmed |
| pubmed-article:8080930 | pubmed:meshHeading | pubmed-meshheading:8080930-... | lld:pubmed |
| pubmed-article:8080930 | pubmed:meshHeading | pubmed-meshheading:8080930-... | lld:pubmed |
| pubmed-article:8080930 | pubmed:meshHeading | pubmed-meshheading:8080930-... | lld:pubmed |
| pubmed-article:8080930 | pubmed:meshHeading | pubmed-meshheading:8080930-... | lld:pubmed |
| pubmed-article:8080930 | pubmed:meshHeading | pubmed-meshheading:8080930-... | lld:pubmed |
| pubmed-article:8080930 | pubmed:meshHeading | pubmed-meshheading:8080930-... | lld:pubmed |
| pubmed-article:8080930 | pubmed:meshHeading | pubmed-meshheading:8080930-... | lld:pubmed |
| pubmed-article:8080930 | pubmed:meshHeading | pubmed-meshheading:8080930-... | lld:pubmed |
| pubmed-article:8080930 | pubmed:meshHeading | pubmed-meshheading:8080930-... | lld:pubmed |
| pubmed-article:8080930 | pubmed:meshHeading | pubmed-meshheading:8080930-... | lld:pubmed |
| pubmed-article:8080930 | pubmed:year | 1994 | lld:pubmed |
| pubmed-article:8080930 | pubmed:articleTitle | Synthesis, characterization and ex vivo evaluation of polydimethylsiloxane polyurea-urethanes. | lld:pubmed |
| pubmed-article:8080930 | pubmed:affiliation | University of Wisconsin-Madison, Department of Chemical Engineering 53706. | lld:pubmed |
| pubmed-article:8080930 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8080930 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
