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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1994-9-30
|
| pubmed:abstractText |
A sensitive and rapid high-performance liquid chromatographic method has been developed for the determination of diclofenac in human serum. The average recovery of diclofenac was 98.2% to 102.5%. The relative standard deviation was 1.29% to 4.52%. The calibration curve was linear in the range from 0.2 microgram/ml to 10.0 micrograms/ml with r = 0.9999. The detection limit of the method was 10 ng/ml. The serum drug concentration-time curve exhibited a 1-compartment open model and the mean T1/2 was 2.15 h.
|
| pubmed:language |
chi
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0513-4870
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
29
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
228-31
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading | |
| pubmed:year |
1994
|
| pubmed:articleTitle |
[High-performance liquid chromatographic method for the determination of diclofenac in serum and its pharmacokinetics in healthy volunteers].
|
| pubmed:affiliation |
Zhujiang Hospital, First Military Medical University, Guangzhou.
|
| pubmed:publicationType |
Journal Article,
English Abstract
|