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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
15
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pubmed:dateCreated |
1994-10-4
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pubmed:abstractText |
Computed tomography (CT) was performed to estimate the density of the hepatic and splenic parenchyma in 18 patients with hemochromatosis. The mean CT density was 79 +/- 21 Hounsfield units compared with 61 +/- 9 (p < 0.01) in 31 controls without hepatic disease. Increased density above 79 Hounsfield units was found in eight patients out of 18 (44%). The highest density (125 Hounsfield units) was found in a patient with a serum ferritin of 6500 micrograms/l. There was an association between CT density and serum ferritin (r = 0.72, p < 0.01). The difference in density between liver and spleen gave better discrimination between patients and controls: 12 of 18 (67%) showed an increased difference in density between liver and spleen. We conclude that CT represents a non-invasive alternative to liver biopsy in cases where the latter is contraindicated. However, CT is not sensitive when serum ferritin is below 1,000 micrograms/l.
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pubmed:language |
nor
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0029-2001
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
10
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pubmed:volume |
114
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1697-9
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pubmed:dateRevised |
2008-7-16
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pubmed:meshHeading |
pubmed-meshheading:8079280-Adult,
pubmed-meshheading:8079280-Aged,
pubmed-meshheading:8079280-Female,
pubmed-meshheading:8079280-Ferritins,
pubmed-meshheading:8079280-Hemochromatosis,
pubmed-meshheading:8079280-Humans,
pubmed-meshheading:8079280-Iron,
pubmed-meshheading:8079280-Liver,
pubmed-meshheading:8079280-Male,
pubmed-meshheading:8079280-Middle Aged,
pubmed-meshheading:8079280-Spleen,
pubmed-meshheading:8079280-Tomography, X-Ray Computed
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pubmed:year |
1994
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pubmed:articleTitle |
[Computer tomography in the detection of hemochromatosis].
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pubmed:affiliation |
Medisinsk avdeling, Aker sykehus, Oslo.
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pubmed:publicationType |
Journal Article,
English Abstract
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