| pubmed-article:8073796 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8073796 | lifeskim:mentions | umls-concept:C0005437 | lld:lifeskim |
| pubmed-article:8073796 | lifeskim:mentions | umls-concept:C0232483 | lld:lifeskim |
| pubmed-article:8073796 | lifeskim:mentions | umls-concept:C1511790 | lld:lifeskim |
| pubmed-article:8073796 | lifeskim:mentions | umls-concept:C0182400 | lld:lifeskim |
| pubmed-article:8073796 | lifeskim:mentions | umls-concept:C1708050 | lld:lifeskim |
| pubmed-article:8073796 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:8073796 | pubmed:dateCreated | 1994-9-29 | lld:pubmed |
| pubmed-article:8073796 | pubmed:abstractText | Currently available methods to assess reflux of duodenal contents into the esophagus are cumbersome, unphysiologic, and inaccurate. The role of intestino-esophageal reflux has therefore been controversial. We assessed intestino-esophageal reflux using a new system which allows prolonged intraesophageal measurement of bilirubin, the major pigment of bile. Measurements were made with a newly developed fiber-optic sensor electrode connected to a portable data processing unit (BILITEC 2000, Synectics Medical Inc., Sweden). Light absorption was measured at the absorption peak of bilirubin and a reference point. Studies were performed in 9 subjects without esophagitis, 9 subjects with esophagitis and primary reflux disease and 7 subjects with erosive esophagitis after a total or subtotal gastrectomy. The fiberoptic electrode was placed 5 cm above the lower esophageal sphincter. In vitro studies showed linear correlations between absorbance measurements obtained with the BILITEC-unit and known bilirubin and bile acid concentrations, respectively (p < 0.01). Compared to both other groups, light absorption was markedly increased in the subjects who had esophagitis after a total or subtotal gastrectomy (p < 0.05) indicating severe biliary reflux. An increase in bilirubin absorption occurred particularly during the post-prandial and supine periodes (p < 0.01). A Roux-en-Y biliary diversion procedure completely abolished bile reflux in 2 of these patients. These data indicate that ambulatory 24-hour fiberoptic measurement of bilirubin in the esophagus is feasible and allows quantitation of intestino-esophageal reflux. Intestino-esophageal reflux occurs particularly during the postprandial period and the early morning hours in patients who had a previous subtotal or total gastrectomy. | lld:pubmed |
| pubmed-article:8073796 | pubmed:language | ger | lld:pubmed |
| pubmed-article:8073796 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8073796 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8073796 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8073796 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8073796 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8073796 | pubmed:month | May | lld:pubmed |
| pubmed-article:8073796 | pubmed:issn | 0044-2771 | lld:pubmed |
| pubmed-article:8073796 | pubmed:author | pubmed-author:SiewertJ RJR | lld:pubmed |
| pubmed-article:8073796 | pubmed:author | pubmed-author:SteinH JHJ | lld:pubmed |
| pubmed-article:8073796 | pubmed:author | pubmed-author:FeussnerHH | lld:pubmed |
| pubmed-article:8073796 | pubmed:author | pubmed-author:KraemerS JSJ | lld:pubmed |
| pubmed-article:8073796 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8073796 | pubmed:volume | 32 | lld:pubmed |
| pubmed-article:8073796 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8073796 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8073796 | pubmed:pagination | 247-51 | lld:pubmed |
| pubmed-article:8073796 | pubmed:dateRevised | 2009-11-11 | lld:pubmed |
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| pubmed-article:8073796 | pubmed:meshHeading | pubmed-meshheading:8073796-... | lld:pubmed |
| pubmed-article:8073796 | pubmed:meshHeading | pubmed-meshheading:8073796-... | lld:pubmed |
| pubmed-article:8073796 | pubmed:meshHeading | pubmed-meshheading:8073796-... | lld:pubmed |
| pubmed-article:8073796 | pubmed:meshHeading | pubmed-meshheading:8073796-... | lld:pubmed |
| pubmed-article:8073796 | pubmed:meshHeading | pubmed-meshheading:8073796-... | lld:pubmed |
| pubmed-article:8073796 | pubmed:year | 1994 | lld:pubmed |
| pubmed-article:8073796 | pubmed:articleTitle | [Quantifying intestino-esophageal reflux with a fiberoptic bilirubin detection probe]. | lld:pubmed |
| pubmed-article:8073796 | pubmed:affiliation | Chirurgische Klinik und Poliklinik, Technische Universität München. | lld:pubmed |
| pubmed-article:8073796 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8073796 | pubmed:publicationType | English Abstract | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8073796 | lld:pubmed |
