Linked Life Data

806946

Source:http://linkedlifedata.com/resource/pubmed/id/806946

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1975-9-29
pubmed:abstractText
Evidence is presented from in vitro experiments in over 1,100 animals that the long accepted hypothesis of a continuous tracheobronchial mucus blanket is untenable, since mucus is transported in the form of flakes, plaques and continuous streams. It is proposed that a liquid of low viscosity lies between the cilia and covers their tips. This liquid is either not transported or very slowly so. Mucus flakes and plaques are transported by the tips of the cilia over this interciliary liquid. Prostaglandin E1 (PGE1) in low concentrations caused lysis of stagnant flakes and plaques. In addition, it caused a marked increase in the quantity of the tracheobronchial fluid and no clear-cut effect on the rate of ciliary frequency. The possible involvement of adenyl cyclase in the response to PGE1 is discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0025-7931
pubmed:author
pubmed:issnType
Print
pubmed:volume
32
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
305-15
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
Mucocililary activity in the respiratory tract as influenced by prostaglandin E.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S.