Linked Life Data

8066978

Source:http://linkedlifedata.com/resource/pubmed/id/8066978

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1994-9-21
pubmed:abstractText
Chloroxylenol, a phenolic derivative commonly used as a household disinfectant, has similar, although lesser, toxic manifestations in comparison to phenol when ingested. The main objective of this study was to determine if chloroxylenol is nephrotoxic like phenol by studying 121 patients with DETTOL (4.8% chloroxylenol, pine oil, isopropyl alcohol) poisoning. Three patients (2.5%) developed renal impairment as evidenced by raised plasma urea and creatinine concentrations following ingestion of 200 to 500 ml of DETTOL. Two of these patients also had serious complications, including aspiration leading to pneumonia and adult respiratory distress syndrome, from which 1 died. The etiology of the renal impairment is likely a direct toxic effect of chloroxylenol on the kidneys and associated transient hypotension. Fortunately, renal impairment only appears to be a problem when relatively large amounts of DETTOL are ingested.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0145-6296
pubmed:author
pubmed:issnType
Print
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
250-1
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Is chloroxylenol nephrotoxic like phenol? A study of patients with DETTOL poisoning.
pubmed:affiliation
Department of Clinical Pharmacology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories.
pubmed:publicationType
Journal Article, Comparative Study, Case Reports