|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
1994-9-12
|
|
pubmed:abstractText |
The chronic effect of PTH on erythrocyte membrane Ca transport was examined. (Ca+Mg)ATPase activity and passive Sr influx were measured to assess the rate of passive Ca influx (total and inhibited by dihydropyridines [DHPs]), in erythrocytes from patients with primary hyperparathyroidism and normal controls. Erythrocyte Sr influx was lower in patients, due to a decreased DHP-sensitive Sr influx. Conversely, efflux activity of (Ca+Mg)ATPase was not different in patients and controls. We hypothesize that in primary hyperparathyroidism chronic PTH stimulation may induce a downregulation of the erythrocyte Ca influx mediated by DHP-sensitive Ca carrier.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Aug
|
|
pubmed:issn |
0006-291X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
15
|
|
pubmed:volume |
202
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1505-10
|
|
pubmed:dateRevised |
2004-11-17
|
|
pubmed:meshHeading |
pubmed-meshheading:8060333-Biological Transport,
pubmed-meshheading:8060333-Ca(2+) Mg(2+)-ATPase,
pubmed-meshheading:8060333-Calcium,
pubmed-meshheading:8060333-Dihydropyridines,
pubmed-meshheading:8060333-Erythrocyte Membrane,
pubmed-meshheading:8060333-Female,
pubmed-meshheading:8060333-Humans,
pubmed-meshheading:8060333-Hyperparathyroidism,
pubmed-meshheading:8060333-Male,
pubmed-meshheading:8060333-Middle Aged,
pubmed-meshheading:8060333-Nitrendipine,
pubmed-meshheading:8060333-Strontium
|
|
pubmed:year |
1994
|
|
pubmed:articleTitle |
Erythrocyte membrane calcium transport in patients with primary hyperparathyroidism.
|
|
pubmed:affiliation |
Department of Nephrology Dialysis and Hypertension, University of Milan, Italy.
|
|
pubmed:publicationType |
Journal Article
|
