Linked Life Data

8054696

Source:http://linkedlifedata.com/resource/pubmed/id/8054696

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
240
pubmed:dateCreated
1994-9-13
pubmed:abstractText
Purified mitochondria from rat brain were incubated in vitro which microtubule-associated proteins (MAPs) that are known to bind specifically on sites present on the outer membrane. The bound molecules were detected by immunoelectron microscopy and the linear distribution of the label along mitochondrial profiles was analyzed by statistical methods. The results demonstrate that gold-conjugated antibodies are distributed in a non-random fashion on the surface of mitochondria, suggesting regional concentrations of MAPs-binding sites. This finding argue for the existence of specialized domains on mitochondria that are involved in the association of the organelles to microtubules in situ.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0376-6160
pubmed:author
pubmed:issnType
Print
pubmed:volume
78
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
47-51
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Statistical analysis of the surface distribution of microtubule-associated proteins (MAPs) bound in vitro to rat brain mitochondria and labelled by 10 nm gold-coupled antibodies.
pubmed:affiliation
U 298 INSERM, CHRU ANGERS.
pubmed:publicationType
Journal Article, In Vitro, Research Support, Non-U.S. Gov't