Linked Life Data

8035767

Source:http://linkedlifedata.com/resource/pubmed/id/8035767

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1994-8-16
pubmed:abstractText
Several evidences suggest the existence of a bidirectional link between the immune and neuroendocrine systems. This relationship explains how a "non cognitive" stimulus (as antigen) can activate the neuroendocrine axis through the inflammatory substances (cytokines) in the same manner as a stress response. A disregulation of this response can determine the basis for a pathological situation. The key-peptide of the stress response is hypothalamic CRF, though also extra-hypothalamic sources, such as the cells of the immune system, are present and could play an important role in the peripheral regulation of stress response.
pubmed:language
ita
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0391-1977
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
19-28
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
[The concept of stress and the role of hypothalamic and extra-hypothalamic corticotropin-releasing factor (CRF) in the integration of the neuroendocrine and immune responses. Clinical and experimental aspects].
pubmed:affiliation
Istituto di I Clinica Medica, Università degli Studi di Roma La Sapienza, Roma.
pubmed:publicationType
Journal Article, English Abstract, Review